Thbs4 reporter mouse
Web24 Jun 2011 · THBS4 is a secreted multidomain glycoprotein of the extracellular matrix belonging to a family of at least five thrombospondins. 37 The only literature record on THBS4 in the scenario of gastric ... Web21 Mar 2024 · THBS4 (Thrombospondin 4) is a Protein Coding gene. Diseases associated with THBS4 include Prostate Cancer and Nephroma . Among its related pathways are PI3K-Akt signaling pathway and Signaling by PDGF . Gene Ontology (GO) annotations related to …
Thbs4 reporter mouse
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Web23 Jan 2024 · We recently reported that TSP-4 promotes angiogenesis 24, 25 and vascular inflammation in a mouse atherosclerosis model 14. These observations suggested that TSP-4 may play an important role in... Web1 May 2024 · The inhibition of THBS4 may provide therapeutic benefits that can prevent the formation of abdominal adhesions. ... Studying the roles of mouse Sox10 by conditional gene targeting.
Web28 Jun 2024 · Thrombospondin-4 (Thbs4) is protective in cardiac and skeletal muscle, where it activates an adaptive endoplasmic reticulum (ER) stress response, induces expansion of the ER, and enhances sarcolemmal stability. Web14 Feb 2024 · For Thbs4 and tTA transgene expressing groups, the Wt sham group contained 2 female and 2 male mice, the Wt TAC group contained 9 female and 3 male mice, the Atf6−/− sham group contained 4 female...
Web22 Jun 2024 · THBS4 is overexpressed both in HCC tissues and cell lines. The overexpression of THBS4 in HCC patients’ samples in contrast to normal samples was first discovered by analysis of StarBase v3.0 (Figure 1A, P = 4.0e-36), which result was identical with the result from analysis of GEPIA (Figure 1B, *P < .01). Furthermore, the expression … Web27 Aug 2013 · This robust postinjury astrogenic response required SVZ Notch (190198) activation modulated by Thbs4 via direct Notch1 receptor binding and endocytosis to activate downstream signals, including increased Nfia (600727) transcription factor expression important for glia production.
WebView In situ reporter (knock in) gene expression results for Thbs4 with structure, expression level, image, reference.
Web1 Sep 2016 · Panel f shows that Thbs4 mRNA is induced in the mouse bladder following 7 days of outlet obstruction. Panel g shows a stack of blots for Thbs4, ATF6α and ATF6α target genes in control and ... pain on top of foot 9 yr old boyWeb8 Jan 2024 · In skeletal muscle, overexpression of Thbs4 dramatically enhanced sarcolemmal stability that rescued mouse models of muscular dystrophy through a mechanism involving enhanced integrin and... submitting a foia requestWeb1 Jul 2014 · The mouse strain B6.129P2-Thbs4 tm1Dgen/J (Thbs4 KO in C57BL/6 background) was obtained from The Jackson Laboratory (Bar Harbor, Maine, USA). In this strain, the Thbs4 gene was inactivated by replacing 14 nucleotides in the first intron with a LacZ-neomycin resistance cassette ... submitting an as1 to the land registryWebThbs4 Mouse Gene Details thrombospondin 4 International Mouse Phenotyping Consortium Gene: Thbs4 MGI:1101779 Not currently registered for phenotyping at IMPC Phenotyping is currently not planned for a knockout strain of this gene. Gene Summary … submitting an amendment irasWebView In situ reporter (knock in) gene expression results for Thbs4 with structure, expression level, image, reference. pain on top of crownWebThbs4 - thrombospondin 4 (house mouse) Predicted to enable several functions, including fibronectin binding activity; heparin binding activity; and laminin-1 binding activity. Involved in behavioral response to pain; regulation of tissue remodeling; and response to endoplasmic reticulum stress. Located in collagen-containing extracellular ... submitting an abstract to a conferencehttp://www.informatics.jax.org/assay/MGI:3639251 submitting an authorization request via efile