Post-translational control of nur77
Web27 May 2024 · Additionally, suppression of Nur77 or NeuroD1 by glucocorticoids is also involved in the glucocorticoid-mediated negative regulation of Pomc in the pituitary [ 16, 20 ]. In our study, dexamethasone-induced decreases in Pomc mRNA levels were partially canceled by Fkbp4 knockdown. WebNR4A1 (also called Nur77, TR3, or NGFIB) is an orphan nuclear receptor that belongs to the steroid/thyroid/retinoid receptor superfamily ( Hazel et al., 1988 ). NR4A1 contains DNA binding domain (DBD) and ligand binding domain (LBD) ( Lin et al., 2004 ), by which NR4A1 is activated and regulates gene expression ( Wu and Chen, 2024 ).
Post-translational control of nur77
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Web24 Jun 2024 · Consequently, MMP activity is tightly regulated through a combination of epigenetic, transcriptional, and post-transcriptional control of gene expression, proteolytic activation, post-translational modifications (PTMs), and extracellular inhibition. In addition, MMPs, their substrates and ECM binding partners are frequently modified by PTMs ... WebNur77 has a ligand-binding pocket that is obstructed by hydrophobic side groups. Naturally occurring, cell-endogenous ligands have not been identified, and Nur77 transcriptional …
WebEnter the email address you signed up with and we'll email you a reset link. WebNur77 as a T cell-intrinsic factor that controls T cell metabolism and T cell-mediated inflammatory diseases. Results Nur77 Restricts Activation and Expansion of T Cells in …
WebPost-translational control can be defined as the mechanisms by which protein structure can be altered after translation. Proteins are polymers of amino acids, and there are twenty different amino acids. Both the order and identity of these amino acids are important for the role that the protein plays in the cell. WebNur77 is a master regulator for Ly6C-monocytes and modulates the inflammatory effect of monocytes and macrophages [ 13, 14 ]. Apoptosis mediated by Nur77 affects thymocyte selection and mature T-cell differentiation. Nur77 also has an effect on T cell tolerance and exhaustion [ 15, 16, 17, 18, 19 ].
WebProduct Name: MEF2A: Chinese Name: 肌细胞增强因子2抗体: Alias: myocyte enhancer-binding factor 2; ADCAD1; MADS box transcription enhancer factor 2 polypeptide A; …
WebCytokine exposure mediates transcriptional activation of the orphan nuclear receptor Nur77 in hematopoietic cells J Biol Chem. 2024 Sep 24;101240. doi: 10.1016/j.jbc.2024.101240. … crtanje maceWebNur77 is a master regulator for Ly6C-monocytes and modulates the inflammatory effect of monocytes and macrophages [ 13, 14 ]. Apoptosis mediated by Nur77 affects thymocyte … crtanje korak po korakWeb18 Sep 2024 · Our findings demonstrate a key role for Nur77 in the maintenance of lung endo- thelial barrier protection to LPS and suggest that therapeutic strategies aimed at … crtanje kuhinje 3dWeb23 Nov 2024 · About. • Data Scientist with 12+ years of experience in conceiving, designing and executing AI- and omics-intensive research projects (basic, translational, pre-clinical … اعلامیه ترحیم خام برای مادرWebPost-translational control of Nur77 (Q62001069) From Wikidata. Jump to navigation Jump to search. scientific article published in December 2006. edit. Language Label Description … crtanje kuhinja u 3d onlineWeb6 Jan 2024 · Post-translational control: Multiple post-translational modifications of EWSR1::FLI1 have been described that regulate transcriptional activity and function in both tempo- and spatial manners . Specifically, EWSR1::FLI1 is phosphorylated at Thr79 in the N-terminal EWSR1 domain upon DNA damage or mitogen stimulations by ERK1/ERK2/JNK … اعلامیه ترحیم خام چهلمWeb3 Sep 2014 · NIH-H460 cells were transfected with control or Nur77 siRNA for 48h, then treated with or without 5 μM apaensin for the indicated time. ... , suggesting its post … اعلامیه ترحیم خام لایه باز