WebJun 18, 2014 · Fluconazole (200 mg) has been used with Busulfan Injection. Decreased clearance of busulfan was observed with concomitant use with deferasirox. The mechanism of this interaction is not fully elucidated. ... Phenytoin increases the clearance of busulfan by 15% or more, possibly due to the induction of glutathione-S-transferase. Since the ... WebFluconazole is used to treat fungal infections, including yeast infections of the vagina, mouth, throat, esophagus (tube leading from the mouth to the stomach), abdomen (area between the chest and waist), lungs, blood, and other organs. Fluconazole is also used to treat meningitis (infection of the membranes covering the brain and spine) caused ...
Fluconazole/phenytoin interaction SpringerLink
WebAug 24, 2024 · Phenytoin: Fluconazole inhibits the hepatic metabolism of phenytoin. Concomitant repeated administration of 200 mg fluconazole and 250 mg phenytoin intravenously, caused an increase of the phenytoin AUC24 by 75% and Cmin by 128%. With coadministration, serum phenytoin concentration levels should be monitored in … WebMar 6, 2024 · Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications. Ritonavir, a strong cytochrome P450 (CYP) 3A4 inhibitor and a P-glycoprotein inhibitor, is coadministered with nirmatrelvir to increase the blood concentration of nirmatrelvir, thereby making it effective against SARS-CoV-2. drawing of nature pencil
Phenytoin Side Effects, Dosage, Uses, and More - Healthline
WebJan 21, 2024 · About 30 medicines for cancer, autoimmune diseases and bleeding disorders include ingredients that may prompt negative reactions with the COVID-19 vaccine. Web• Functional group elucidation to learn degradant products in fluconazole, phenytoin, levodopa using Nicolet™iS™5 FTIR • Worked on Labconco Freezone 4.5 freeze dryer, for lyophilization of WebMar 19, 2024 · Diltiazem and verapamil are both moderate-weak inhibitors of CYP3A4 and substrates for P-gp. Use of immediate-release verapamil just before dabigatran leads to … employment equity forms 2021 south africa